What is the normal range for AFP?

An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).

What is a normal AFP level at 20 weeks?

Maternal AFP levels in pregnancy start to rise from about 14th week of gestation up until about 32 weeks gestation. Between week 15 and 20 weeks, levels usually range between 10 ng/ml to 150 ng/ml. Adult blood levels of greater than 200 ng/ml in patients with liver cirrhosis strongly indicate hepatocellular carcinoma.

How do you read AFP results?

Alpha fetoprotein normal range is below ten ng/ml. In the case of adults who aren’t pregnant, if the results show that there is a high level of AFP, then it indicates that you have liver disease. The AFP levels fluctuate throughout pregnancy. In pregnant women, a higher AFP level indicates Spina bifida in your fetus.

What can raise AFP levels?

Outside of pregnancy and birth, liver damage and certain cancers can increase AFP levels significantly. This test measures the level of AFP in your blood. AFP is produced whenever liver cells are regenerating. With chronic liver diseases, such as hepatitis and cirrhosis, AFP may be chronically elevated.

What is a low AFP level in pregnancy?

Low levels of AFP and abnormal levels of hCG and estriol may indicate the developing baby has Trisomy 21( Down syndrome), Trisomy 18 (Edwards Syndrome) or another type of chromosome abnormality. Abnormal levels may also be a result of the following: A multiples pregnancy.

What are high AFP levels in pregnancy?

A positive test with a high AFP suggests a birth defect like spina bifida. That’s typically a result of 2.5 times or more than the “average” level of AFP you’d expect to see at that point in your pregnancy.

What do AFP numbers mean?

AFP stands for alpha-fetoprotein. It is a protein made in the liver of a developing baby. AFP levels are usually high when a baby is born, but fall to very low levels by the age of 1. Healthy adults should have very low levels of AFP. An AFP tumor marker test is a blood test that measures the levels of AFP in adults.

What causes AFP levels to rise?

AFP levels are normally elevated when a baby is born and then decline rapidly. Outside of pregnancy and birth, liver damage and certain cancers can increase AFP levels significantly. This test measures the level of AFP in your blood. AFP is produced whenever liver cells are regenerating.

What is the reference value for AFP in pregnancy?

Reference values are for nonpregnant subjects only; fetal production of AFP elevates values in pregnant women. Range for newborns is not available, but concentrations over 100,000 ng/mL have been reported in normal newborns, and the values rapidly decline in the first 6 months of life.

When do AFP levels return to normal after birth?

AFP is elevated during pregnancy. Persistence of AFP in the mother following birth is a rare hereditary condition.(2) Neonates have markedly elevated AFP levels (>100,000 ng/mL) that rapidly fall to below 100 ng/mL by 150 days and gradually return to normal over their first year.(2) Concentrations of AFP above…

How are serum alpha fetoprotein levels measured in babies?

Serum alpha fetoprotein (AFP) levels in normal infants Serum alpha-fetoprotein (AFP) levels were monitored in 32 normal babies consecutively from 2 to 3 days, 2 wk, and 2 and 4 months after birth. In addition, serum AFP concentration was also measured in 116 random specimens from infants with normal liver enzymes and 10 infants born immaturely.

Can a healthy adult have low AFP levels?

Healthy adults should have very low levels of AFP. An AFP tumor marker test is a blood test that measures the levels of AFP in adults. Tumor markers are substances made by cancer cells or by normal cells in response to cancer in the body.