What is the formulation of suspension?
What is the formulation of suspension?
The formulation of a suspension depends on whether the suspension is flocculated or deflocculated in nature. However, there are three common approaches that are applied to formulate a suspension. These are 1) Controlled flocculation, 2) Structured vehicle and 3) Controlled flocculation in the structured vehicle.
What are the components used for formulating a pharmaceutical suspension?
Choice of pH, particle size, viscosity, flocculation, taste, color and odor are some of the most important factors that must be controlled at the time of formulation. The various components, which are used in suspension formulation, are as follows. continuous liquid phase.
What is suspension in pharmaceuticals?
A pharmaceutical suspension is a coarse dispersion of insoluble solid particles in a liquid medium. The particle diameter in a suspension is usually greater than 0.5 µm. In addition, when compared to solution dosage forms, relatively higher concentration of drugs can be incorporated into suspension products.
What are the pharmaceutical applications of suspension?
The suspension dosage form has long been used for insoluble and poorly soluble drugs for making oral, topical and parenteral products. Pharmaceutical Suspensions, From Formulation Development to Manufacturing provides the reader with a broad overview of suspension drug product technology.
How many types of suspension are there in pharmacy?
Based on the route of administration, suspensions can be classified as oral, topical, ophthalmic, otic, or nasal suspensions. Each of these present unique challenges and requirements in terms of desired quality attributes.
What is a suspension example?
Ans: Common examples of suspension include the mixture of chalk and water, muddy water, the mixture of flour and water, a mixture of dust particles and air, fog, milk of magnesia, etc. Particles of the suspension are large enough to scatter the rays of light and the path of ray is visible through it.
What are the 10 examples of suspension?
Examples of Suspension
- Muddy water.
- Milk of magnesia.
- Sand particles suspended in water.
- Flour in water.
- Slaked lime for whitewashing.
- Paints in which dyes are suspended in turpentine oil.
What is an example of a suspension?
Give some examples of suspension. Ans: Common examples of suspension include the mixture of chalk and water, muddy water, the mixture of flour and water, a mixture of dust particles and air, fog, milk of magnesia, etc. In it, particles of the solute do not dissolve in the solution and are rather suspended.
How are suspensions used in the pharmaceutical industry?
Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients sus- pended in a suitable vehicle.
Which is a patent for an oral suspension formulation?
US5112604A – Oral suspension formulation – Google Patents An aqueous suspension for oral administration of a drug, which suspension is storage stable for a prolonged period and maintains the drug in suspension during such period.
What kind of solvent is used for pharmaceutical suspensions?
The most commonly used vehicle for the formulation of pharmaceutical suspensions is purified water. In a few instances, viscous nonaqueous solvents, such as propylene glycol and polyethylene glycols, are used as vehicles to impart stability to suspended drug particles.
How big is the particle size of a pharmaceutical suspension?
Typically, the suspensions with particle size greater than ~1 mm are classified as coarse suspension, while those below 1 mm are classified as colloidal suspension. When the particles constituting the internal phase of the suspension are therapeutically active, the suspension is known as pharmaceutical suspension.