What is Libman sack?

Libman–Sacks endocarditis (LSE) is a form of non-bacterial endocarditis that is seen in association with systemic lupus erythematosus (SLE), antiphospholipid syndrome, and malignancies. It is one of the most common heart-related manifestations of lupus (the most common being pericarditis).

Which valve is affected more in Libman sack endocarditis?

The left-sided valves are involved most often, with a higher preference for the mitral valve followed by the aortic valve. Libman-Sacks Endocarditis. Transesophageal image of a mitral valve with masses characteristic of Libman-Sacks endocarditis.

What is a sterile vegetation?

Sterile vegetations form on heart valves in response to factors such as trauma, circulating immune complexes, vasculitis, or a hypercoagulable state. The sterile vegetations can embolize or become infected but rarely impair valvular or cardiac function.

What causes marantic endocarditis?

Marantic endocarditis (a.k.a. non-bacterial thrombotic endocarditis or NBTE) occurs from deposition of thrombus and fibrinous material on the heart valves, most commonly the mitral valve. This is frequently associated with hypercoagulable states, adenocarcinomas and systemic lupus erythematosus.

Is endocarditis a terminal?

Outlook and prevention. Untreated endocarditis is always fatal, but with early treatment, involving an aggressive use of antibiotics, most patients survive.

What is vegetation on the heart valve?

Abnormal growths (vegetations) that contain collections of bacteria may form in your heart at the site of the infection and damage the heart valves, which can cause them to leak. Endocarditis is a life-threatening inflammation of the inner lining of your heart’s chambers and valves (endocardium).

Who was the patient with Libman Sacks endocarditis?

Case report of a 19 year-old female patient with systemic lupus erythematosus (SLE) who was presented to Ain Shams University Hospital complaining of dyspnea on moderate exertion. Echocardiography showed the presence of sterile vegetation on the mitral valve, Libman–Sacks endocarditis (LSE).

What kind of prednisone for Libman endocarditis?

Echo-Doppler study was done at that time revealing normal LV dimensions and function with EF = 60%, and a mild circular pericardial effusion. Treatment was initiated with prednisone 1 mg/kg/day, with the improvement of her symptoms. However, the patient interrupted the treatment for one year.

Is there a cure for left sided native valve endocarditis?

(See “Culture-negative endocarditis: Epidemiology, microbiology, and diagnosis” and “Antimicrobial therapy of left-sided native valve endocarditis” and “Clinical manifestations and evaluation of adults with suspected left-sided native valve endocarditis” .)

What is the best treatment for nonbacterial thrombotic endocarditis?

Prompt antimicrobial therapy should be initiated if there is any clinical suspicion for infective endocarditis. Otherwise, treatment includes corticosteroids (prednisone 1 mg/kg per day), but a consensus on a specific regimen is unclear.