What is hyper-CVAD chemotherapy?

An abbreviation for a chemotherapy combination used to treat some types of acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL). Hyper-CVAD includes the drugs cyclophosphamide, vincristine sulfate, doxorubicin hydrochloride (Adriamycin), and dexamethasone.

What is hyper-CVAD Part B?

Each of the medications in HyperCVAD (Part B) (methotrexate + cytarabine) are designed to kill cancer cells in the blood stream and bone marrow. Goals of therapy: To eliminate leukemia cells from the body and to decrease symptoms from ALL, such as bleeding, bruising, and recurrent infections.

Is nelarabine a chemotherapy?

Drug Type: Nelarabine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “antimetabolite.” (For more detail, see “How Nelarabine Works” below).

What type of drug is asparaginase?

Enzyme
Asparaginase/Classification
Drug type: Asparaginase is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “enzyme.” (For more detail, see “How this drug works” section below).

Does nelarabine cause hair loss?

The “normal” cells will grow back and be healthy but in the meantime, side effects occur. The “normal” cells most commonly affected by chemotherapy are the blood cells, the cells in the mouth, stomach and bowel, and the hair follicles; resulting in low blood counts, mouth sores, nausea, diarrhea, and/or hair loss.

How is hyper CVAD used to treat cancer?

Acute lymphoblastic leukemia (certain types). Non-Hodgkin lymphoma (certain types). Hyper-CVAD is given as hyperfractionated therapy, in which the total daily dose is divided into smaller doses and given more than once a day. This combination may also be used with other drugs or treatments or to treat other types of cancer.

How often can you take hyper-CVAD for lymphoma?

Non-Hodgkin lymphoma (certain types). Hyper-CVAD is given as hyperfractionated therapy, in which the total daily dose is divided into smaller doses and given more than once a day. This combination may also be used with other drugs or treatments or to treat other types of cancer.

How long does it take for Hyper CVAD to work?

You have chemotherapy as a course of several sessions (cycles) of treatment over a few months. With hyper-CVAD, you have two different schedules of treatment called A and B. You will have each schedule four times in a pattern of A then B. Each cycle of hyper-CVAD lasts 21 days.

Where can I get Hyper-CVAD for leukemia?

1 Departments of Leukemia, Biomathematics, and Radiotherapy, M.D. Anderson Cancer Center, Houston, TX 77030, USA. Purpose: To evaluate the efficacy and toxicity of Hyper-CVAD (fractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone), a dose-intensive regimen, in adult acute lymphocytic leukemia (ALL).