What is danazol used to treat?

Hear this out loudPauseDanazol is in a class of medications called androgenic hormones. It works to treat endometriosis by shrinking the displaced tissue of the uterus. It works to treat fibrocystic breast disease by blocking the release of hormones that cause the breast pain and lumps.

What is the side effect of danazol?

Hear this out loudPauseSide Effects Weight gain, acne, flushing, sweating, voice changes (hoarseness, change in pitch), abnormal growth of body hair (in women), vaginal dryness/irritation, or decreased breast size may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Is danazol a painkiller?

Hear this out loudPauseDanazol is a synthetic steroid used to treat pelvic pain and infertility due to endometriosis, and also to treat breast pain/tenderness/nodules due to fibrocystic breast disease. Danazol is available in generic form.

Does danazol stop menstruation?

Hear this out loudPauseDanazol has a multitude of effects on the body. Some of these effects combine to produce high levels of androgen and low levels of oestrogen in the body. This hormonal environment stops menstruation and suppresses the growth of endometrial implants, causing them to degenerate [1,2].

When should I take danazol?

Hear this out loudPauseStart taking danazol on the first day of your period unless you have been told otherwise. You can take the capsules either before or after meals. It is important that you do not become pregnant while on danazol.

How long can you take danazol?

Hear this out loudPauseIt is essential that therapy continue uninterrupted for 3 to 6 months but may be extended to 9 months if necessary. After termination of therapy, if symptoms recur, treatment can be reinstituted.

Is danazol a birth control?

Hear this out loudPauseThe effect of Danazol as an oral contraceptive in doses of 50, 100, and 200 mg daily for 6 months was studied in 3 groups of 10 women. Both 50 and 100 mg Danazol daily were well tolerated, but one pregnancy occurred among the women receiving 50 mg daily, and 2 pregnancies occurred in women receiving 100 mg daily.

Can danazol cause PCOS?

Hear this out loudPauseThe effects of danazol on ovarian steroidogenesis and follicular size was studied in androgen-sterilized rats bearing polycystic ovaries. Daily treatment with 4 or 20 mg of the drug caused a reduction in ovarian weight and regression of cystic follicles.

How does danazol reduce estrogen?

Hear this out loudPauseDanazol competitively inhibits estrogen and progesterone receptors in the breast, hypothalamus, and pituitary82; inhibits multiple enzymes of ovarian steroidogenesis83; inhibits the midcycle surge of LH in premenopausal women; and reduces gonadotropin levels in postmenopausal women.

Can danazol cause diabetes?

Hear this out loudPauseInsulin-dependent diabetes mellitus developed in a young woman 8 weeks after the initiation of danazol for treatment of pelvic endometriosis. After discontinuation of danazol the diabetes completely resolved. We suspect a possible cause-and-effect relationship, which has not previously been reported in the literature.

Can danazol cause infertility?

Hear this out loudPauseIt can cause cysts and infertility. Danazol is a hormone that produces male characteristics as well as weight gain and acne. It does, however, relieve the painful symptoms of endometriosis, although the side effects can be unacceptable.

What do you need to know about danazol capsules?

Danazol capsules are indicated for the prevention of attacks of angioedema of all types (cutaneous, abdominal, laryngeal) in males and females.

Are there any side effects to taking danazol in utero?

Exposure to Danazol in utero may result in androgenic effects on the female fetus; reports of clitoral hypertrophy, labial fusion, urogenital sinus defect, vaginal atresia, and ambiguous genitalia have been received (see PRECAUTIONS, Pregnancy, Teratogenic Effects ).

How is danazol used to treat endometriosis?

Danazol is used to treat endometriosis. Danazol is also used to treat attacks of hereditary angioedema (an immune system disorder). Danazol reduces bradykinin production and could potentially reduce the impact of a bradykinin storm. Bradykinin storms may be responsible for some of the complications experienced by COVID-19 patients.

How is danazol used to treat hereditary angioedema?

Danazol is also used to treat attacks of hereditary angioedema (an immune system disorder). Danazol reduces bradykinin production and could potentially reduce the impact of a bradykinin storm. Bradykinin storms may be responsible for some of the complications experienced by COVID-19 patients.