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How do you synthesize phenylacetone?

How do you synthesize phenylacetone?

Synthesis. One method of creating phenylacetone is via: phenylacetic acid (C8H8O2) + acetic anhydride (C4H6O3) + pyridine catalyst → phenylacetone (C9H10O) + carbon dioxide (CO2) + water (H2O) Sodium acetate has been used instead of pyridine.

Is phenylacetone a controlled substance?

Phenylacetone is a DEA Schedule II controlled substance.

What drug is P2P?

P2P. The principal chemicals are phenyl-2-propanone, aluminum, methylamine, and mercuric chloride. This method yields lower quality dl-methamphetamine, has been associated with outlaw motorcycle gangs (OMGs), and is commonly referred to as the P2P method.

What is BMK oil?

Short description BMK Oil | PMK Oil is the deamination product of amphetamine metabolism and has been used as a precursor in the illicit synthesis of methamphetamine.

How do you make yeast from ephedrine?

But to make ephedrine, the chemical benzaldehyde is added to the mix; the yeast ferments the benzaldehyde to produce an intermediate product called PAC, which is extracted using organic solvents, and then the PAC is converted into ephedrine in a second catalytic reaction which also requires the use of solvents.

Can you make phenylacetone from acetone enolate?

Phenylacetone from acetone enolate is a reaction that’s been very well covered, since its such a classic, simple Sn1 reaction to study. The reagents are cheap, and its all pretty straight forward. Because of this, a ton of variations have been investigated, and a lot have progress has been made.

What kind of acid is used to make phenylacetone?

There are a myriad of ingenious methods of making phenylacetone – some starting with phenylacetic acid, some with benzyl chloride, and dozens of others.

Why is acetic anhydride important in phenylacetic acid reaction?

In this reaction, it is important that acetic anhydride is present in the reaction mixture in a large molar excess over the phenylacetic acid. If the ratio is too small, the phenylacetone will condense with itself to form useless Dibenzyl Ketone .

What makes phenylacetone a Schedule 2 controlled substance?

Phenylacetone is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence. Phenylacetone is a propanone that is propan-2-one substituted by a phenyl group at position 1. It is a member of propanones and a methyl ketone.